Vitamin D is the Best Weapon Against Crohn"s Disease!
Scientists from McGill University and the Univeriste de Montreal discovered that Vitamin D, in its purest form, can counteract the effects of Crohn's disease, a form of inflammatory bowel disease (IBD), (Journal of Biological Chemistry). It involves ongoing or chronic inflammation of the gastrointestinal tract. The Crohn's-induced inflammation most often affects the intestines. However, it may also occur at the mouth and rectum, (ADAM Multimedia Encyclopedia).
The exact cause of Crohn's disease was unknown until now. Now that scientists have extensively studied this disease, they now have a better understanding of how it affects the body. It has long been suspected that Crohn's disease is linked to a malfunction of the body's immune system response, but it was not clear how, (ADAM Multimedia Encyclopedia). That assumption wasn't farfetched.
In fact, in the process of determining that Vitamin D has a direct effect on Crohn's disease, the scientists realized that the innate immune system, which acts as the body's first defense against microbial invaders was the part of the immune system that was directly involved with the disease. It is believed that the immune system is overreacting to normal bacteria in the intestines, (ADAM Multimedia Encyclopedia).
Findings from the study suggest, for the first time, that Vitamin D deficiency can directly contribute to Crohn's disease. There is even a belief that people from northern countries who receive less sunlight necessary for the manufacture of Vitamin D by the human body, are susceptible to Crohn's disease, (Journal of Biological Chemistry). According to ADAM Multimedia Encyclopedia, genetic predisposition and environmental factors seem to play a large role in a person getting Crohn's disease.
The research team found that Vitamin D acts directly on the beta defensin 2 gene. This gene encodes for an antimicrobial peptide. Vitamin D also acts directly on the NOD2 gene, which alerts cells to the presence of invading microorganisms that enters the body, according to the research team. They said both Beta-defensin and NOD2 have been linked to Crohn's disease, suggesting that if NOD2 is deficient or defective, it won't be able to combat invading microbes in the intestinal track.
Vitamin D, in its active form is called "1, 25-dihydroxyvitamin D," which is a hormone that binds to receptors of cells of the body, according to the researchers. Over-the-counter Vitamin D Supplements can adequately supply the body with enough Vitamin D, the team said.
The researchers argued that the Crohn's-Vitamin D discovery can be put to the test, stating that siblings of people with Corhn's disease who haven't yet developed the disease might be well advised to make sure they are Vitamin D sufficient, and they can get enough Vitamin D in their systems by simply going to the pharmacy and buying Vitamin D supplements.
It is great to know that Vitamin D can help people defend themselves against Crohn's disease or other inflammatory bowel diseases by them just buying Vitamin D supplements from the local pharmacy.
The exact cause of Crohn's disease was unknown until now. Now that scientists have extensively studied this disease, they now have a better understanding of how it affects the body. It has long been suspected that Crohn's disease is linked to a malfunction of the body's immune system response, but it was not clear how, (ADAM Multimedia Encyclopedia). That assumption wasn't farfetched.
In fact, in the process of determining that Vitamin D has a direct effect on Crohn's disease, the scientists realized that the innate immune system, which acts as the body's first defense against microbial invaders was the part of the immune system that was directly involved with the disease. It is believed that the immune system is overreacting to normal bacteria in the intestines, (ADAM Multimedia Encyclopedia).
Findings from the study suggest, for the first time, that Vitamin D deficiency can directly contribute to Crohn's disease. There is even a belief that people from northern countries who receive less sunlight necessary for the manufacture of Vitamin D by the human body, are susceptible to Crohn's disease, (Journal of Biological Chemistry). According to ADAM Multimedia Encyclopedia, genetic predisposition and environmental factors seem to play a large role in a person getting Crohn's disease.
The research team found that Vitamin D acts directly on the beta defensin 2 gene. This gene encodes for an antimicrobial peptide. Vitamin D also acts directly on the NOD2 gene, which alerts cells to the presence of invading microorganisms that enters the body, according to the research team. They said both Beta-defensin and NOD2 have been linked to Crohn's disease, suggesting that if NOD2 is deficient or defective, it won't be able to combat invading microbes in the intestinal track.
Vitamin D, in its active form is called "1, 25-dihydroxyvitamin D," which is a hormone that binds to receptors of cells of the body, according to the researchers. Over-the-counter Vitamin D Supplements can adequately supply the body with enough Vitamin D, the team said.
The researchers argued that the Crohn's-Vitamin D discovery can be put to the test, stating that siblings of people with Corhn's disease who haven't yet developed the disease might be well advised to make sure they are Vitamin D sufficient, and they can get enough Vitamin D in their systems by simply going to the pharmacy and buying Vitamin D supplements.
It is great to know that Vitamin D can help people defend themselves against Crohn's disease or other inflammatory bowel diseases by them just buying Vitamin D supplements from the local pharmacy.
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